Endometriosis Immunopathology: The Macrophage Connection

Endometriosis Immunopathology: The Macrophage Connection By Ayse Ayhan

Macrophages and tiny signaling particles called extracellular vesicles (EVs) are emerging as central immune players in how endometriosis develops and persists. Together, they shape the immune environment around endometriotic lesions, helping them survive, spread, and resist the body’s defenses. In…

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Macrophage Phenotypes Induced by Circulating Extracellular Vesicles in Endometriosis

Macrophage Phenotypes Induced by Circulating Extracellular Vesicles in Endometriosis By Hakan Kula

In a study published in the Biomolecules, Martínez-Zamora et al. investigated the potential effect of circulating sEVs in the plasma of well-characterized patients with endometriosis on macrophage phenotype.  This study explores how sEVs, which are tiny particles found in the blood of women…

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Inflammatory and genetical background of endometriosis may yield new therapeutic approaches

Inflammatory and genetical background of endometriosis may yield new therapeutic approaches By Nasuhi Engin Aydin

Elisa Giacomini and colleagues from medical centers in Milan, Italy have published their review manuscript on the inflammatory and genetical pathogenetic background of endometriosis in a recent issue of  “International Journal of Molecular Sciences”, suggesting also new therapeutic approaches. The inflammatory…

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Exosome: a new avenue for endometriosis research

Exosome: a new avenue for endometriosis research By Dr. Youngran Park

Endometriosis affects 10% of reproductive-aged women. The pathophysiology of this disease remains mysterious, with a lack of effective biomarkers necessitating surgical intervention for diagnosis. This creates an urgent need for accurate noninvasive diagnostic tests and the identification of effective therapeutic…

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